KSTEM’s Course Registration Tips

It’s that time of year again where clicking, typing, and being a human at 11:15AM has never seemed more stressful. That’s right: it’s course registration. I asked KSTEM president Rachel Arens to gather the best registration tips around.

Note: The following is a guest post from KSTEM, a club on campus with a mission to develop a strong and supportive scientific community. Email stem@kenyon.edu for more information!

  1. Register in the science quad with as few people as possible! Registration works smoothly if there aren’t many people per router.
  2. Make sure you have at least two classes that you are genuinely excited about.
  3. If there’s one class that you really need/want and is difficult to get into just put that class in first and hit submit; you don’t have to waste time filling up the slots before you hit submit the first time!
  4. Make an excel sheet or Google Sheet so you can copy and paste!
  5. Minimize your windows so they’re side by side and you don’t have to click between
  6. Tell Duo NOT to remember you for 10 hours so it’s easier to log in and log out.
  7. If there’s a popular class you really want, email the professor ahead of time asking to be in the class/put on the waitlist!
  8. IT’S ALL GOING TO WORK OUT! Don’t panic! Everything will be ok.

Know Before You Go – Metagenomics Edition

Today (yes, October 12th!) at 4 PM, Dr. Heidi Andersen from Cincinnati Children’s Hospital Medical Center will be presenting her bioinformatics research. Computational genomics is a rapidly advancing field that uses and develops software to detect patterns in biomolecules like DNA, RNA, and proteins. Our guts host many different bacterial species, and Dr. Andersen pieces together their DNA sequences to determine which are present. She is especially interested in tracking the microbes that are multi-drug resistant (those that survive many of the antibiotics we throw at them) across pediatric patients in the hospital. 

A quick brush up on some computational biology vocab before the presentation never hurts:

Metagenomics – the study of the many genomes present in a given environmental sample

Microbiome – the community of microbes in a given environment

Shotgun sequencing – a method of determining the order of nucleotides (A, C, T, G) in a given DNA sequence by breaking it into short fragments, sequencing these, then piecing them back together computationally

Contiguous sequence (“Contig”) – After sequencing the separate DNA fragments in shotgun sequencing, we need to assemble them back together for a longer, more complete sequence (a contig)

16S rRNA gene (“16S”) – a ribosomal RNA gene that is used to identify bacteria and archaea at the genus level

Extra credit – Understanding PCA
If you want to know all the gory details of Principal Component Analysis, a method you will see often in computational biology, check out this post here

 

The Very Hungry Hornworms

This week, intro bio lab students geared up for their Manduca sexta dissection. These tobacco hornworms had grown significantly since students placed them in their plastic “bachelor pad” cages last week. While all hornworms at least doubled in size, the largest of the group were almost 100 times their weight from last week. Thank goodness that’s pretty impossible for humans to do or Kenyon would need to invest in a better health plan now that Marco’s Pizza accepts K-Cards.

Hornworm fact #1: Time to expand your insult dictionary – the genus Manduca literally means glutton. Try that one at Thanksgiving.

Hornworm fact #2: After a good chomp on a tobacco leaf, Manduca have “toxic halitosis” aka poisonous bad breath from the nicotine which deters spiders from eating them.

Hornworm fact #3: Adult Manduca hawkmoths can eavesdrop on the sonar clicks of bats and drop out of the air to avoid being bat food.

If you know the story of The Very Hungry Caterpillar by Eric Carle, the life of a Manduca is quite similar. Rather than eating sausages and ice cream turning into a beautiful butterfly, though, Manduca hornworms eat the leaves of tobacco, tomatoes and other members of the nightshade family (Solanaceae), then metamorphose into a hawkmoth that can hover like a hummingbird. Reared in the lab, however, the Manduca is a beloved model organism with ease of care, rapid growth rate, and accessible anatomy.

This year, the bio lab sections are testing the effect of diet nutrition on overall growth of the organism. Some Manduca will have less nutrition per bite in their food for 48 hours, perhaps affecting how much they eat, absorb nutrients, or grow in a 48 hour period. After this diet change, students hit the microscopes to investigate.

Whether they named their Manduca after their TA (shoutout to Jeremy Moore ’19), took beautiful anatomical pictures under the microscope (see above), or made a video in their hornworm’s honor like Patrick Olmstead ’21 (below), students found a way to connect with their lab-reared pe(s)ts.